با توجه به اهمیت دیتابیس‌ها در آنالیز داده‌های NGS تصمیم گرفتیم که تعدادی از دیتابیس‌های مورد نیاز شما در مسیر آنالیزها را در اینجا در دسترس شما برای دانلود قرار دهیم. از این موارد در انواع پایپلاین‌ها میتوانید استفاده کنید.

راستی اگر دیتای خاصی مدنظرتون بود که فکر میکردید خوب میشه که روی سرورمون قرار بگیره تا برای شما هم دانلودش راحت بشه در بخش دیدگاه‌ها برامون بنویسین.

موفق باشین

میلاد

Databases

Base quality score recalibration (BQSR) database, Source: Broad Institute, dbSNP146, hg19: Download

Base quality score recalibration (BQSR) database, Source: Broad Institute, dbSNP146, hg38: Download

Variant quality score recalibration (VQSR) databases, Source: Broad Institute, hg38, all in one file: Download

Variant quality score recalibration (VQSR) databases, Source: Broad Institute, hg19, all in one file: Download

BWA-mem indexed genome, Source: Illumina, GRCh37: Download

af-only-gnomad Germline resource for somatic variant calling using mutect2 pipeline, Source: Broad Institute, GRCh37, optional, chr-embedded: Download

af-only-gnomad Germline resource for somatic variant calling using mutect2 pipeline, Source: Broad Institute, GRCh37, optional, chr-not-embedded: Download

Human Genome FASTA file, hg19: Download

Bismark indexed genome, mm10, Mus musculus: Download

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-Some of the ANNOVAR local databases which they are not publicly or easily available:

hg19, Iranome : Download

hg38, Iranome: Download

CADD version 1.6: Firstly, Download ALL the parts (66GBs) and put all of them along each other in a folder, then using WinRAR tool extract part1(It doesn’t need to extract each part individually). The huge CADD database file and its index will be generated as large as about 345 GBs. So, take care about your hard disk space! (The links are tested.)

Part1 – Part2 – Part3 – Part4 – Part5 – Part6 – Part7 – Part8 – Part9 – Part10 – Part11 – Part12 – Part13 – Part14 – Part15 – Part16 – Part17

COSMIC version 92, Coding and non-Coding variants, hg19: Download

ClinVar databases (It is recommended to use only the latest version of it):

2023.04.16 :version date: , Clinvar database, hg19: Download

2023.04.16 :version date, Clinvar database, hg38: Download

2023.07.2 :version date, Clinvar database, hg19: Download

2023.07.2 :version date, Clinvar database, hg38: Download

2023.09.23 :version date, Clinvar database, hg19: Download

2023.09.23 :version date, Clinvar database, hg38: Download

2023.12.09 :version date, Clinvar database, hg19: Download

2023.12.09 :version date, Clinvar database, hg38: Download