NGS و بیوانفورماتیک

Clinical CNV Analysis in NGS Data

Learn a practical CNV workflow for NGS data—from paired-end preparation and ExomeDepth calling to structured review and interpretation.

Milad Eidi 6 lessons
Clinical CNV Analysis in NGS Data
Free
Login to Enroll

30-Day Money-Back Guarantee

What You'll Learn

  • Understand CNVs and the principal approaches used to investigate them
  • Prepare paired-end data and perform CNV calling with ExomeDepth
  • Review results using the ACMG/ClinGen concepts introduced in the course

About This Course

Learn how copy-number variants can be investigated in NGS data. The course begins with core CNV concepts and detection approaches, then guides you through data preparation, calling, review, and interpretation.

The material is organized into four focused stages, with course datasets and a supplementary session available in the curriculum for continued practice.

A four-stage CNV workflow

  • Concepts and environmentUnderstand CNVs, compare detection approaches, and set up a virtual Linux environment.
  • Data preparationExplore sequencing simulation, paired-end alignment, and repeatable processing with loops.
  • CNV callingCreate FASTA genome indexes and dictionaries and learn the ExomeDepth workflow.
  • Review and interpretationEvaluate results and review the ACMG/ClinGen framework introduced in the course.

Who is this course for?

  • Students and researchers interested in CNV analysis from sequencing data.
  • Professionals who understand the general NGS workflow and want to expand into copy-number analysis.

Related learning

Recommended preparation

  • Basic familiarity with FASTQ files, alignment, and aligned-read formats is recommended.
  • Comfort with Linux and stepwise data preparation will help with the exercises.

Curriculum 2 sections

  • دوره آنالیز بالینی CNV در داده‌های NGS - قسمت ۱
  • دوره آنالیز بالینی CNV در داده‌های NGS - قسمت ۲
  • دوره آنالیز بالینی CNV در داده‌های NGS - قسمت ۳
  • دوره آنالیز بالینی CNV در داده‌های NGS - قسمت ۴

  • دوره آنالیز بالینی CNV در داده‌های NGS - لایو اینستاگرام
  • دیتاهای دوره

Quizzes

  • آزمون نهایی دوره آنالیز CNVها در داده‌های NGS 12 questions

Quizzes open once you are enrolled in the course.

Student Reviews

No reviews yet. Be the first to review this course!

Instructor
Milad Eidi
Milad Eidi
Bioinformatics Expert

Experienced instructor in bioinformatics and computational biology.

Course Details
  • 2 sections
  • 6 lessons
  • Full lifetime access